Publication
In collaboration with academic research groups, there is part of a number of publications on specific Blockmirs and their potential therapeutic use:
Targeting vascular endothelial-cadherin in tumor-associated blood vessels promotes T cell-mediated immunotherapy
Yang Zhao, Kaka Ting, Jia Li, Victoria C Cogger, Jinbiao Chen, Anna Johansson-Percival, Shin Foong Ngiow, Jeff Holst, Georges E. R. Grau, Shom Goel, Thorleif Moller, Elisabetta Dejana, Geoffrey W McCaughan, Mark J. Smyth, Ruth Ganss, Mathew A Vadas and Jennifer R Gamble
Cancer Research DOI: 10.1158/0008-5472.CAN-16-3129
Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin–restricted miRNA antagonists of miR-27
Jennifer A. Young, Ka Ka Ting, Jia Li, Thorleif Moller, Louise Dunn, Ying Lu, Angelina J. Lay, Joshua Moses, Leonel Prado-Louren?o, Levon M. Khachigian, Martin Ng, Philip A. Gregory, Gregory J. Goodall, Anna Tsykin, Ilana Lichtenstein, Christopher N. Hahn, Nham Tran, Nicholas Shackel, James G. Kench, Geoffrey McCaughan, Mathew A. Vadas and Jennifer R. Gamble
Blood 2013 122:2911-2919; doi: https://doi.org/10.1182/blood-2012-12-473017
Therapeutic regulation of VE-cadherin with a novel oligonucleotide drug for diabetic eye complications using retinopathy mouse models
Ka Ka Ting, Yang Zhao, Weiyong Shen, Paul Coleman, Michelle Yam, Tailoi Chan-Ling, Jia Li, Thorleif Moller, Mark Gillies, Mathew A. Vadas, Jennifer R. Gamble
Diabetologia. 2018 Nov 15. doi: 10.1007/s00125-018-4770-4.
The VE-Cadherin/β-catenin signalling axis regulates immune cell infiltration into tumours
Yang Zhao, Jia Li, KaKa Ting, Jinbiao Chen, Paul Coleman, Ken Liu, Li Wan, Thorleif Moller, Mathew A. Vadas, Jennifer R. Gamble
Cancer Letters, Volume 496, 1 January 2021, Pages 1-15
Targeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice
Jia Li Yang Zhao, Jaesung Choi, Ka Ka Ting, Paul Coleman, Jinbiao Chen, Victoria C. Cogger, Li Wan, Zhongsong Shi, Thorleif Moller, Xiangjian Zheng, Mathew A. Vadas, Jennifer R. Gamble
PLOS Biology | https://doi.org/10.1371/journal.pbio.3000734 June 5, 2020
